Mifekit-Mifepristone and Misoprostol 200mg

How It Works 

Mifepristone and misoprostol use is a two-step method.

• In the first place, your specialist provides for you a measurements of mifepristone tablets by mouth. Mifepristone causes the placenta to partitioned from the endometrium. It additionally relaxes the cervix and increments uterine constrictions to permit the uterine substance to pass.

• Second, you take tablets of misoprostol by mouth or addition them vaginally, generally inside 48 hours of mifepristone. Contingent upon the measurement and how it is given, this could be when 6 hours after the mifepristone.1 Some specialists may give misoprostol buccally (disintegrated between the gums and cheek). Misoprostol causes uterine constrictions with the goal that your body passes the uterine substance. Numerous specialists permit their patients to take misoprostol at home and after that the pregnancy finishes (like an unnatural birth cycle) at home.

A medicinal premature birth typically requires no less than two visits to your specialist over a few weeks. For the first visit, one pharmaceutical is taken amid the visit and a second medication is given to be taken at home. The second visit is a catch up arrangement, normally booked around 2 weeks after the first visit, to verify the pregnancy has finished and no inconveniences are available. In the event that a therapeutic premature birth is not effective, a surgical fetus removal is then done to finish the methodology in light of the fact that misoprostol can result in fetal variations from the norm.

You can take ache prescription by mouth for this medicinal system.

How Well It Works

Medical abortions can be done through 9 weeks of pregnancy. Up to 7 weeks, the combination of mifepristone (orally) and misoprostol (orally) is effective in about 92 out of 100 cases.¹

Inside 4 hours of taking the second prescription (misoprostol), numerous ladies have vaginal draining and cramping, and the pregnancy is terminated.2 Most pregnancies end inside the initial 24 hours after the misoprostol measurements. If not, then ordinarily a second dosage of misoprostol is given.

Misoprostol can be given orally, buccally (disintegrated between the gums and cheek), or vaginally. Misoprostol is marginally more compelling when given vaginally than when taken by mouth.But numerous specialists are just giving misoprostol by mouth on account of reports of an uncommon, deadly contamination that influenced a couple of ladies in the wake of utilizing vaginal misoprostol. A few studies have demonstrated that taking misoprostol buccally functions and also when it is given vaginally or orally.

Side Effects

This method of abortion causes symptoms similar to a miscarriage (such as severe cramping and vaginal bleeding) as tissue and clots pass from the uterus. Symptoms may include:

• Nausea.
• Vomiting.
• Diarrhea.
• Headache.
• Dizziness.
• Chills or hot flushes (sweating and feeling overly hot).
• Shivering.
• Fatigue.

Side effects may increase as the length of pregnancy increases and in women having their first pregnancy.

The U.S. Food and Drug Administration (FDA) has reported that a few women have died from a severe infection (sepsis) after having an abortion using mifepristone and vaginal misoprostol.⁵ Signs of serious infection include weakness, nausea, and diarrhea with or without belly pain. This rare infection may not cause a fever. Call your doctor or go to the hospital if you have any of these signs of a serious infection after having a medical abortion.

Signs of complications

Call your doctor immediately if you have any of these symptoms after an abortion:

• Severe bleeding. Both medical and surgical abortions usually cause bleeding that is different from a normal menstrual period. Severe bleeding can mean:
  • Passing clots that are bigger than a golf ball, lasting 2 or more hours.
  • Soaking more than 2 large pads in an hour, for 2 hours in a row.
  • Bleeding heavily for 12 hours in a row.
• Signs of infection in your whole body, such as headache, muscle aches, dizziness, or a general feeling of illness. Severe infection is possible without fever.
• Severe pain in the abdomen that is not relieved by pain medicine, rest, or heat.
• Hot flushes or a fever of 100.4°F (38°C) or higher that lasts longer than 4 hours.
• Vomiting lasting more than 4 to 6 hours.
• Sudden abdominal swelling or rapid heart rate.
• Vaginal discharge that has increased in amount or smells bad.
• Pain, swelling, or redness in the genital area.

Call your doctor for an appointment if you have had any of these symptoms after a recent abortion:

• Bleeding (not spotting) for longer than 2 weeks.
• New, unexplained symptoms that may be caused by medicines used in your treatment.
• No menstrual period within 6 weeks after the procedure.
• Signs and symptoms of depression. Hormonal changes after a pregnancy can cause depression that requires treatment.

See Drug Reference for a full list of side effects. (Drug Reference is not available in all systems.)

What To Think About

Choosing a medical or surgical procedure for an abortion will depend on your medical history, how many weeks pregnant you are, what options are available where you live, and your personal preferences.

Mifepristone should not be used for women who have any of the following conditions:²

• Adrenal failure
• Allergy to mifepristone
• Severe anemia
• Bleeding disorders or use of blood thinners (anticoagulants)
• Long-term corticosteroid use
• Suspected ectopic pregnancy
• Heart disease or uncontrolled high blood pressure (hypertension)
• Intrauterine device (IUD) in place
• Liver or kidney disease
• Undiagnosed ovarian mass
• Respiratory diseases
• Inherited skin diseases

Avoid alcohol and aspirin while using mifepristone and misoprostol for a medical abortion.

A medical abortion does not require surgery but must be done in the first 9 weeks of pregnancy. If a medical abortion fails, a surgical abortion must be done as follow-up.

After a medical abortion

Expect that you may experience different emotional reactions after an abortion.

Depression can be triggered when pregnancy hormones change after an abortion. If you have more than 2 weeks of depression symptoms, such as fatigue, sleep or appetite change, or feelings of sadness, emptiness, anxiety, or irritability, see your doctor about treatment.

Do not have sexual intercourse for at least 1 week, or longer, as advised by your doctor.

When you start having intercourse again, use birth control, and use condoms to prevent infection. For more information, see the topic Birth Control.

Your next regular period may come at any time within 6 weeks after the abortion. Be sure to contact your doctor if you do not have a period within 6 weeks.